Is there a link between Peyronie's disease and cancer?

Although Peyronie’s disease is a benign condition (non-carcinogenic), it is common to have questions about its possible consequences and its relationship with other diseases.

One of these questions is whether there is a link between Peyronie’s disease and cancer. Can it develop into a tumor? Is there an increased risk of developing certain types of cancer? As Peyronie’s disease experts, we explain what is currently known.

Can Peyronie's disease develop into cancer?

No. Peyronie’s disease is not cancerous and does not develop into cancer.

The plaques that form in the penis consist of scar tissue, not malignant cells. Although they can cause deformities and affect erectile function, they should not be confused with a tumor.

The causes of Peyronie’s disease are associated with various factors, including microtrauma, abnormal healing processes, and genetic predisposition.

Peyronie's disease and cancer: what does science say?

Although Peyronie’s disease does not directly cause cancer, some studies have investigated whether there is a possible association between the two conditions.

A study published in 2019 in the journal Sexual Medicine, involving more than 48,000 men with Peyronie’s disease, found a statistical association with certain types of cancer:

  • Testicular cancer.
  • Stomach cancer.
  • Melanoma, a type of skin cancer.

However, there is an important distinction: just because two diseases are associated does not mean that one causes the other.

At present, these findings do not establish a causal relationship.

Dolor en el pene por Peyronie

Does having Peyronie's disease mean a higher risk of cancer?

Not necessarily. Although some studies have observed a relative increase in the risk of certain tumors, there is still insufficient evidence to consider Peyronie’s disease an independent risk factor for cancer.

Furthermore, individual cancer risk depends on numerous factors, such as age, family history, and lifestyle habits.

Therefore, having Peyronie’s disease does not mean that additional routine cancer screening is necessary. The most important thing is to follow recommended health check-ups and seek medical advice for any new or persistent symptoms.

How can you tell if a change in the penis is cause for concern?

Not all lumps or hardened areas in the penis have the same origin. While Peyronie’s disease typically presents with fibrous plaques and curvature during an erection, other conditions may cause different changes.

It is important to pay attention to certain warning signs:

  • Progressive curvature or pain during an erection.
  • Lumps or hardened areas that appear in the penis.
  • Wounds, ulcers, or lesions that do not heal.
  • Persistent skin changes or unexplained bleeding.

These symptoms do not necessarily indicate the presence of cancer, but they do warrant a medical evaluation to identify their cause.

Síntomas de la enfermedad peyronie

Peyronie's disease specialists in Barcelona

Although Peyronie’s disease is not a cancerous disease, understanding its progression and distinguishing its symptoms from other conditions is essential for maintaining men’s health.

At Andrología Barcelona, we have specialists in andrology and urology who provide individualized assessments to identify the cause of symptoms and evaluate possible treatment options.

If you have noticed changes in your penis or have questions about Peyronie’s disease, our team can help address your concerns.

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